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Health and Human Services Department National Institutes of HealthFederal RegisterMed source confidence · 81%Jun 25, 2026, 9:34 AM UTC · 13d ago

Government Owned Inventions Available for License: C8166-45 Cell Line

Case File

The National Institutes of Health's National Cancer Institute is offering a license for a human T-cell line known as C8166-45, which is transformed by HTLV-1. This cell line, also referred to as C63/CRII-2, has three active proviruses that can help in studying T-cell growth and immortalization. The effective date for this notice is June 25, 2026.

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Why This Matters

The availability of the C8166-45 T-cell line for licensing provides researchers with a valuable tool for studying T-cell behavior, which could lead to better cancer treatments. The June 25, 2026, effective date allows time for interested parties to prepare their applications.

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